Changes in antimicrobial resistance and outcomes of health care–associated infections

Aydın M., Azak E., Bilgin H., Menekse S., Asan A., Mert H. T. E., ...Daha Fazla

European Journal of Clinical Microbiology and Infectious Diseases, cilt.40, sa.8, ss.1737-1742, 2021 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 8
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1007/s10096-020-04140-y
  • Dergi Adı: European Journal of Clinical Microbiology and Infectious Diseases
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, CAB Abstracts, EMBASE, Environment Index, MEDLINE, Public Affairs Index, Veterinary Science Database
  • Sayfa Sayıları: ss.1737-1742
  • Anahtar Kelimeler: associated infections, Blood stream infections, Colistin resistance, Health care
  • Trakya Üniversitesi Adresli: Evet

Özet

To describe the change in the epidemiology of health care–associated infections (HAI), resistance and predictors of fatality we conducted a nationwide study in 24 hospitals between 2015 and 2018. The 30-day fatality rate was 22% in 2015 and increased to 25% in 2018. In BSI, a significant increasing trend was observed for Candida and Enterococcus. The highest rate of 30-day fatality was detected among the patients with pneumonia (32%). In pneumonia, Pseudomonas infections increased in 2018. Colistin resistance increased and significantly associated with 30-day fatality in Pseudomonas infections. Among S. aureus methicillin, resistance increased from 31 to 41%.