Anaphylactic reaction to lansoprazole Lansoprazole karşi anaflaktik reaksiyon
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi, cilt.35, sa.3, ss.209-211, 2007 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 35 Sayı: 3
- Basım Tarihi: 2007
- Dergi Adı: Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.209-211
- Anahtar Kelimeler: Anaphylactic reactions, Lansoprazole
- Trakya Üniversitesi Adresli: Evet
Özet
Lansoprazole is a substituted benzimidazole that has gained widespread use in the treatment of acidic and peptic ulcer disease. Adverse events with the drug are rare and involve mainly the gastrointestinal and central nervous systems. Skin inflammation, urticaria, pruritus, alopecia, and dry skin have been reported in 0.5-1.5 % of patients. We report a case of a 56-year-old man with peptic ulcers who developed periorbital edema, edema of the skin, generalized pruritis and urticaria, a swollen tonque, increase sweating and loss of conciousness. These findings suggest that the chemically related lansoprazole can, as a group, cause anaphylactic reactions; however, the rate is comparatively low. Since anaphylaxis is a potentially serious reaction, more precise information is needed regarding its frequency, and healthcare professionals need to be aware of this possibility when prescribing these agents.