A comparison of esmolol alfentanyl, fentanyl and lidocaine for attenuation cardiovascular response to laryngoscopy and tracheal intubation Laringoskopi ve trakeal entubasyonla gelisen kardiyovaskuler yanitlarin onlenmesinde esmolol, alfentanil, fentanil ve lidokainin karsilastirilmasi
Turk Anesteziyoloji ve Reanimasyon, cilt.27, sa.9, ss.513-516, 1999 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 27 Sayı: 9
- Basım Tarihi: 1999
- Dergi Adı: Turk Anesteziyoloji ve Reanimasyon
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.513-516
- Anahtar Kelimeler: Alfentanyl, Esmolol, Fentanyl, Haemodynamic response, Laryngoscopy, Lidocaine, Tracheal intubation
- Trakya Üniversitesi Adresli: Evet
Özet
This study was designed to compare the efficacy of esmolol, alfentanyl, fentanyl and lidocaine for cardiovascular responses to laryngoscopy and tracheal intubation. Fifty ASA physical status class I-II patients undergoing elective surgery were included in a randomized study consisting of 5 groups with each group receiving a designated drug: Group A received esmolol (0.8 mg/kg), Group B alfentanyl (10 μg/kg), Group C fentanyl (2 μg/kg), Group D lidocaine (1.5 mg/kg) and Group E saline (10 mL) as control. Heart rate, mean arterial pressure (MAP) and peripheric oxygen saturation values were recorded after injection of the drugs, immediately before laryngoscopy and after tracheal intubation. HR, MAP and SpO2 values were not significantly different after injection the drugs in all groups (p>0.05). HR values after tracheal intubation were significantly higher in C, D, E groups (p<0.05) but no difference in A and B groups (p>0.05). MAP values after tracheal intubation were significantly higher in all groups (p<0.05). SpO2 values were similar in all groups (p>0.05). As a result of our study, we conclude that esmolol (0.8 mg/kg) and alfentanyl (10 g/kg) are safe and effective for controlling the increase of HR during laryngoscopy and tracheal intubation.