Brain atrophy and hypomyelination associated with iatrogenic cushing syndrome in an infant

Dogan S., DOĞAN M. D., TÜTÜNCÜLER KÖKENLİ F., Yapiciugurlar O., Genchellac H.

Iranian Journal of Child Neurology, cilt.12, sa.1, ss.101-104, 2018 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.22037/ijcn.v12i1.12395
  • Dergi Adı: Iranian Journal of Child Neurology
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.101-104
  • Anahtar Kelimeler: Brain atrophy, Diaper dermatitis, Iatrogenic cushing syndrome, Magnetic resonance imaging, Myelination
  • Trakya Üniversitesi Adresli: Evet

Özet

Prolonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We herein report a 5-month-old female infant referred to Department of Pediatric Endocrinology, Edirne, Turkey with brain atrophy and myelination delay that might be due to iatrogenic Cushing syndrome caused by topical corticosteroid use.