Clinical Nuclear Medicine, cilt.26, sa.4, ss.363-364, 2001 (SCI-Expanded, Scopus)
A case of bone metastasis from a primary splenic angiosarcoma to the sacrum is presented. A 70-year-old woman was hospitalized because of weight loss of 25 kg in 4 months and left upper quadrant pain. Physical examination revealed a palpable spleen 15 cm below the left costal margin and a painful sacrum. Ultrasonographic examination showed that the spleen was markedly enlarged, with a heterogeneous low-echo pattern. Doppler evaluation revealed increased vascularization. The computed tomographic scan showed a hypodense parenchyma with nodular and tubular enhancement after contrast administration. The spleen was removed, and the histopathologic diagnosis was primary angiosarcoma of the spleen. The findings of Tc-99m MDP bone imaging were consistent with a metastasis in the sacrum. Tc-99m RBC imaging showed increased uptake in the sacral metastasis.