Predicting Lamina Propria Invasion in Patients with Nonmuscle-invasive Bladder Cancer: Do RDW and NLR Really Work?

senturk a. b., Ekici M., aydin c., baykam m. m., Tas T., Arda E., ...Daha Fazla

Üroonkoloji Bülteni, cilt.18, sa.1, ss.6-9, 2019 (TRDizin) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4274/uob.galenos.2018.1099
  • Dergi Adı: Üroonkoloji Bülteni
  • Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.6-9
  • Trakya Üniversitesi Adresli: Evet

Özet

Objective: To determine the role of preoperative neutrophil-to-lymphocyte ratio (NLR) and red cell distribution width (RDW) in predicting laminapropria invasion in bladder cancer.Materials and Methods: Eighty-eight patients with non-muscle-invasive bladder cancer were evaluated retrospectively. The patients were dividedinto those with Ta tumors (group 1: n=36) and those with T1 tumors (group 2: n=52). For each patient, white blood cell, neutrophil, and leukocytecounts and RDW values were evaluated.Results: NLR was significantly lower in patients with Ta tumors. In addition, NLR below 3.22 was associated with 80.6% probability of Ta disease.RDW sensitivity in Ta non-muscle-invasive bladder tumors was much higher compared to T1 tumors. RDW below 15.35 was associated with 94.4%probability of Ta disease.Conclusion: NLR and RDW are basic blood parameters that physicians can assess easily. Our results indicate that a combination of NLR and RDW canhelp clinicians predict lamina propria invasion in non-muscle-invasive bladder tumors.