The Relationship Between Cardiorespiratory Function and Disease Severity, Pain and Fatigue Parameters in Fibromyalgia Syndrome
NAMIK KEMAL MEDICAL JOURNAL, cilt.13, sa.4, ss.419-426, 2025 (ESCI, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 4
- Basım Tarihi: 2025
- Doi Numarası: 10.4274/nkmj.galenos.2025.62134
- Dergi Adı: NAMIK KEMAL MEDICAL JOURNAL
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.419-426
- Trakya Üniversitesi Adresli: Evet
Özet
Aim: The objective of the present study is to examine the effects of fibromyalgia on cardiorespiratory and autonomic nervous system functions, as well as quality of life, in fibromyalgia patients. Materials and Methods: The study included 39 women aged 25-50 years with fibromyalgia syndrome and 39 women without fibromyalgia as a control group. Fibromyalgia impact questionnaire, pain score with visual analogue scale, widespread pain index, symptom severity scale, fibromyalgia severity scale, Beck depression inventory, fatigue severity scale, 6-minute walk test and 24-hour blood pressure monitoring with Holter device were applied to all participants. Results: The comparative analysis revealed that patients suffering from fibromyalgia exhibited a diminished 6-minute walking distance, with values recorded at 492.26 +/- 53.95 meters, significantly lower than the control group's mean of 550.13 +/- 44.56 meters (p<0.05). While heart rate recovery index was comparable, fibromyalgia patients had a higher prevalence of non-dipper blood pressure patterns (26.9% vs. 11.5%, p<0.05). Higher fibromyalgia severity scale scores were associated with greater fatigue severity scale (r=0.619, p<0.001) and Beck depression inventory scores (r=0.457, p<0.001), and inversely correlated with 6-minute walking distance (r=-0.444, p<0.001). The fibromyalgia impact questionnaire scores were correlated with fatigue severity scale scores (r=0.717, p<0.001) and Beck depression inventory scores (r=0.541, p<0.001), but not with 6-minute walking distance (r=-0.069, p=0.675). Conclusion: The study found that women with fibromyalgia have impaired physical capacity and autonomic nervous system function compared to those without the condition. This highlights the importance of periodically assessing circadian blood pressure rhythms in people with fibromyalgia. Furthermore, the study suggests that fatigue and depressed mood are more impactful for individuals with fibromyalgia than physical limitations.