Effects of antibiotic solutions (ciprofloxacin and trimethoprim + sulphamethoxazole) on rabbit tympanic membrane

Karasolihoglu A., Adali M., KOTEN M., ŞEKER V., Kutlu K.

Revue de Laryngologie Otologie Rhinologie, cilt.116, sa.2, ss.153-156, 1995 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 116 Sayı: 2
  • Basım Tarihi: 1995
  • Dergi Adı: Revue de Laryngologie Otologie Rhinologie
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.153-156
  • Anahtar Kelimeler: antibiotic solutions, ciprofloxacin, trimethoprim + sulphamethoxazole, tympanic membrane
  • Trakya Üniversitesi Adresli: Evet

Özet

This study was designed to assess morphological changes in the rabbit tympanic membrane after ciprofloxacin and trimethoprim + sulphamethoxazole had been instilled as a single dose into the middle ear cavities of 24 rabbits. At different times the rabbits were decapitated and the lesions which occured on the tympanic membrane were studied histopathologically. Our results indicate that in the ciprofloxacin group reactive inflammatory changes are reversible as in the trimethoprim + sulphamethoxazole group.