Akademik Veri Yönetim Sistemi
Journal of Clinical Obstetrics & Gynecology, cilt.29, sa.3, ss.94-99, 2019 (Scopus, TRDizin)
Objective: To investigate the etiology, obstetric risk factors, complications, and outcomes of pregnancies affected by thrombocytopenia. Material and Methods: A retrospective surveillance study was conducted based on the hospital records of 1286 women that gave birth duringthe period between 1st January 2017 and 31st December 2018 at the Department of Gynecology andObstetrics of the Trakya University’s School of Medicine. Clinical data including basic history,physical examination, and investigations of women with thrombocytopenia were evaluated. Werandomly selected 154 patients without thrombocytopenia that delivered in our clinic during thesame period, as the control group, and compared the maternal and fetal outcomes with the thrombocytopenic patient group. Results: A total of 154 out of 1286 women (11.9%) had thrombocytopenia of varying severity. Gestational thrombocytopenia (GT) was the most common cause, beingidentified in 76.2% of the cases with thrombocytopenia. This was followed by preeclampsia (15.5%).About 4.5% of pregnant women with thrombocytopenia were accounted for by idiopathic thrombocytopenic purpura (ITP), 2.5% of the patients by eclampsia, while HELLP (hemolysis, elevatedliver enzymes, and low platelets) syndrome was observed in 1.3% of the pregnant women withthrombocytopenia. An increased rate of IUGR (Intrauterine growth restriction), fetal distress, andadverse neonatal outcomes were recorded among patients that had thrombocytopenia withpreeclampsia, eclampsia, and HELLP syndrome. Furthermore, we observed higher rates of fetal distress and adverse neonatal outcomes in patients with thrombocytopenia compared to the controlgroup. Conclusion: GT was the most common cause of thrombocytopenia in pregnancy, followedby preeclampsia. Eclampsia, HELLP syndrome, and ITP were rare causes of this disorder duringpregnancy. Early detection and treatment of expected complications are critical for the effectivemanagement of such cases.