Evaluation of left ventricular function with strain/strain rate imaging in patients with rheumatic mitral stenosis
ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.10, sa.4, ss.328-333, 2010 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 10 Sayı: 4
- Basım Tarihi: 2010
- Doi Numarası: 10.5152/akd.2010.091
- Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
- Sayfa Sayıları: ss.328-333
- Trakya Üniversitesi Adresli: Hayır
Özet
Objective: The most important sequel of acute rheumatic fever is mitral stenosis in long-term. The aim of the study is to determine left ventricular (LV) functions by tissue Doppler imaging (TDI) and strain/strain rate echocardiography (SE/SRE) in mitral stenosis patients who had no clinical signs of heart failure. Methods: Our study was designed as cross-sectional study. The study population consisted of 32 patients with isolated mitral stenosis and mitral valve area <2.0 cm(2) (Group 1) and 25 healthy control subjects (Group 2). In addition to standard echocardiographic methods, TDI and SE/SRE were performed to assess LV functions in all participants. Student's t-test was used to compare continuous variables. Fisher- exact test was used to compare categorical variables. Results: Systolic myocardial velocity (Sm) were significantly lower in Group 1 than in Group 2 (6.0 +/- 1.4 cm/sec vs 7.9 +/- 1.8 cm/sec, p<0.001) also, early diastolic myocardial velocity (Em) were significantly lower in Group 1 than in Group 2(4.4 +/- 1.5 cm/sec vs 10.8 +/- 2.1 cm/sec, p<0.001). But there was no significant difference in late diastolic myocardial velocity (Am) between two groups. Peak systolic strain and strain rate of septal wall in Group 1 were significantly lower than Group 2 (p<0.001 for both). Besides, peak systolic strain and strain rate of lateral wall in Group 1 were significantly lower than in Group 2 (p<0.001 for both). Conclusion: Although, global ejection fraction was normal and there were no symptoms of heart failure clinically in the patients with mitral stenosis, LV dysfunction demonstrated that using by echocardiography. TDI and strain/strain rate imaging to be new echocardiographic methods may be used reliably for detection LV function in early stage of mitral stenosis. (Anadolu Kardiyol Derg 2010; 10:328-33)