The development of Hodgkin lymphoma in male patient with systemic lupus erythematosus and secondary antiphospholipid syndrome Sistemik lupus eritematozus ve sekonder antifosfolipid sendromlu bir erkek hastada Hodgkin lenfoma gelişimi: Bir olgu sunumu ve literatürü n gözden geçirilmesi

PAMUK G. E., Pamuk Ö. N., Tekgündüz E., TURGUT B., Demir M., ÇAKIR N.

UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi, cilt.17, sa.1, ss.37-41, 2007 (Scopus, TRDizin) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 1
  • Basım Tarihi: 2007
  • Dergi Adı: UHOD - Uluslararasi Hematoloji-Onkoloji Dergisi
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.37-41
  • Anahtar Kelimeler: Hodgkin's lymphoma, Lymphadenopathy, Secondary antiphospholipid syndrome, Systemic lupus erythematosus
  • Trakya Üniversitesi Adresli: Evet

Özet

There are some data that the frequency of malignancy increases in some autoimmune diseases. The development of Hodgkin's lymphoma in patients with systemic lupus erythematosus (SLE) has been reported rarely. Here, we presented a young male SLE patient who had recurrent thrombophlebitis and deep venous thrombosis, secondary antiphospholipids syndrome, and who has been using cyclophosphamide and corticosteroids for 1.5 years for lupus nephritis. After a follow-up of 1.5 years, he developed fever, night sweats and lymphadenopathy. Lymph node biopsy was compatible with mixed-cellular type Hodgkin's lymphoma, and he was in complete hematologic remission after ABVD chemotherapy. Although SLE is a disease which may cause lymphadenopathy and B symptoms, when these symptoms develop in a SLE patient in remission, lymph node biopsy should be taken to rule out the possibility of lymphoma.