Late-onset clozapine-induced neutropenia treated with lithium


Creative Commons License

Durmus P. T., GÖRGÜLÜ Y., SÖNMEZ M. B., Cinar R. K.

Dusunen Adam - The Journal of Psychiatry and Neurological Sciences, cilt.32, sa.1, ss.74-77, 2019 (Scopus, TRDizin)

Özet

Clozapine is a second-generation antipsychotic drug, proven to be effective in treatment-resistant schizophrenia. Among patients using clozapine; the incidence of neutropenia is approximately 3% and the incidence of agranulocytosis is approximately 1%. This side effect is diminishing after 18 weeks of drug initiation. Here, we present a case of clozapine-induced neutropenia in a schizophrenic patient seen after 7 years of clozapine use and its treatment with lithium supplementation.