Initial presentation of an unspecified peripheral T-cell lymphoma as inflammatory polyarthritis and hypereosinophilia
European Journal of Oncology, cilt.21, sa.3, ss.174-179, 2016 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21 Sayı: 3
- Basım Tarihi: 2016
- Dergi Adı: European Journal of Oncology
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.174-179
- Anahtar Kelimeler: Arthritis, Hypereosinophilia, Lymphoma, Peripheral T-cell lymphoma-unspecified (PTCL-U), Rheumatoid arthritis (RA)
- Trakya Üniversitesi Adresli: Evet
Özet
Summary. Premise: There may be signs of joint and bone involvement in hematologic malignancies, but it is most rare for hematologic malignancies like lymphomas to present with joint symptoms. Patient: A 49-year-old male patient was admitted with rheumatoid arthritis-like symmetrical polyarthritis, morning stiffness, cutaneous vasculitis and hypereosinophilia. Autoantibodies, like rheumatoid factor, anti-citrullinated cyclic peptide, antinuclear antibody, anti-nuclear cytoplasmic antibody, were negative. After 4 months of follow-up, the patient developed a diffuse cutaneous rash and multiple lymphadenopathies. Lymph node biopsy was compatible with peripheral T-cell lymphoma, unspecified. Result: The patient was administered, respectively, CHOP and ICE chemotherapy regimens to which he was refractory. He died from infection and respiratory failure. Conclusion: It should be borne in mind that T-cell lymphomas may have unusual presentations with arthritis and hypereosinophilia.