Does vaginal preparation with povidone-iodine prior to caesarean delivery reduce the risk of endometritis A randomized controlled trial
Journal of Maternal-Fetal and Neonatal Medicine, cilt.25, sa.11, ss.2316-2321, 2012 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 25 Sayı: 11
- Basım Tarihi: 2012
- Doi Numarası: 10.3109/14767058.2012.693994
- Dergi Adı: Journal of Maternal-Fetal and Neonatal Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.2316-2321
- Anahtar Kelimeler: Caesarean delivery, Endometritis, Povidoneiodine
- Trakya Üniversitesi Adresli: Evet
Özet
Objective: The purpose of the present study was to determine whether the vaginal preparation with povidoneiodine prior to caesarean delivery decreased the incidence of postpartum endometritis. Methods: The present study was a prospective randomized controlled trial in which subjects received a vaginal preparation with povidoneiodine solution immediately prior to caesarean delivery or received no vaginal preparation. The primary outcome measure was the rate of postpartum endometritis. Results: A significant decrease in post-caesarean endometritis was noted in the group that received the povidoneiodine vaginal preparation (n = 334) compared with the control group (n = 336) [6.9 vs. 11.6%; RR = 1.69; 95% CI = 1.032.76]. No statistically significant differences in the incidence of endometritis were noted between the experimental and control groups among women who were not in labor at the time of the caesarean delivery [9.2 vs. 8.6%; RR = 1.05; 95% CI = 0.581.90], and no differences were found between groups when women with ruptured membranes were excluded from the analysis [9.6 vs. 6.7%; RR = 1.39; 95% CI = 0.782.47]. Conclusions: Vaginal preparation with povidoneiodine solution immediately prior to a caesarean delivery reduces the risk of post-operative endometritis. This preemptive measure was only found to be beneficial in women whose membranes had ruptured and those who were in labor prior to caesarean surgery. © 2012 Informa UK, Ltd.