Cisatracurium given by intermittent bolus or infusion methods for muscle relaxation in ICU Cisatrakuryumun aralikli bolus veya i̇nfüzyon uygulamasinin yoǧun bakim hastalarinda kas gevşemesine etkileri
Turk Anesteziyoloji ve Reanimasyon, cilt.29, sa.2, ss.69-72, 2001 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 29 Sayı: 2
- Basım Tarihi: 2001
- Dergi Adı: Turk Anesteziyoloji ve Reanimasyon
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.69-72
- Anahtar Kelimeler: Cisatracurium, Intensive care unit, Muscle relaxants, Paralysis, TOF monitorisation
- Trakya Üniversitesi Adresli: Evet
Özet
We aimed to compare in our study, cisatracurium continuous infusion or intermittent IV bolus in 28 patients who needed musculer relaxation for at least 10 h in ICU, the patients were randomly divided into two equal groups and monitored by TOF. In group I; IV bolus cisatracurium 0.2 mg/kg was given. After the T95 (beginning time for effect) achieved, time for the next incremental muscle relaxant was noted. Recovery time after last given dosege was noted, time achieved to T70 (recovery index), and amount of muscle relaxant administered for the study was noted. In group II; After the T95 achieved (beginning time for effect) 2 μg/kg/min cisatracurium infusion was started. At the end of the procedure, recovery time after the end of cisatracurium infusion, time achieved to T70 (recovery index) and amount of muscle relaxant applied for the study was noted. The study time was 15±3.8 and 18.3±4.8 in group I and II respectively (p>0.05). In Group I through study time cisatracurium dose 4.42±1.6 μg/kg, in Group II was applied as 3.07±0.9 μg/kg/min IV (p<0.01). Recovery times were 87.64±11.5 minutes in Group I, and 38.38±5.4 minutes in Group II (p<0.01).