Gogus-Kalp-Damar Anestezi ve Yogun Bakim Dernegi Dergisi, cilt.12, sa.3, ss.113-118, 2006 (Scopus)
The aim of this study was to evaluate the effect of adding sevoflurane to cardiopulmonary bypass pump on analgesic consumption and postoperative recovery in coronary artery surgery. Sixty two patients who underwent elective cardiopulmonary bypass surgery were included in this study. Standart premedication, monitorisation and anesthetic induction was applied to all patients. Anesthesia was maintained with 5-10 μg.kg-1 fentanyl i.v. until cardiopulmoner bypass. Patients assigned into two groups during cardiopulmonary bypass, anesthesia was maintained with adding 5 μg.kg-1 fentanyl Group I (n=31) or 0.5-1.5 MAC sevoflurane to cardiopulmonary bypass pump. After cross-clamping anesthesia was maintained with 1-1.5 MAC sevaflurane and pancuronium. Hemodynamic parameters were recorded in different times. The fentanyl consumption and duration of anesthesia, operation, total bypass and extubation of the patient were recorded. Intraoperative fentanyl dosage and extubation time was significantly low in Group II. There was no significantly difference in terms of stay at the ICU between groups. Finally, we concluded that adding sevoflurane to cardiopulmonary bypass pump provides intraoperative low dose fentanyl consumption and early extubation besides intraoperative and postoperative hemodynamic stability so that it is a good alternative for coronary artery bypass grafting surgery.