Fulminant hepatitis-A in a child using sodium valproate therapy: Case report Sodyum valproat tedavisi alan bir çocukta fulminan hepatit-A
Turkiye Klinikleri Pediatri, cilt.19, sa.2, ss.176-179, 2010 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 19 Sayı: 2
- Basım Tarihi: 2010
- Dergi Adı: Turkiye Klinikleri Pediatri
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.176-179
- Anahtar Kelimeler: Child, Hepatic encephalopathy, Hepatitis A, Hepatitis A vaccines, Liver failure, acute, Valproic acid
- Trakya Üniversitesi Adresli: Evet
Özet
The risk of fulminant liver failure due to hepatitis A infection increases in the patients with underlying chronic liver diseases and hepatotoxic drug-use. In this case report, we aimed to emphasize the development of fulminant liver failure due to hepatitis A infection and importance of hepatitis A vaccination in these cases. A five-year age boy who treated with sodium valproate for three years was admitted with the symptoms of fulminant liver failure and encephalopathy to our emergency clinic. Hepatitis A IgM-antibody was found positive and serum sodium valproate level was mildly elevated. In conclusion, fulminant progression risk due to hepatitis-A infection increase in the patients using hepatotoxic drug such as sodium valproate. Therefore, hepatitis-A vaccination for these cases is important for decreasing the risk of fulminant hepatitis. Copyright © 2010 by Türkiye Klinikleri.