Functional association of interleukin-18 gene -607 C/A promoter polymorphisms with endometriosis


AYAZ L., Çelik S. K., Çayan F., Aras-Ate N., Tamer L.

Fertility and Sterility, cilt.95, sa.1, ss.298-300, 2011 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 95 Sayı: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.fertnstert.2010.07.1046
  • Dergi Adı: Fertility and Sterility
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.298-300
  • Anahtar Kelimeler: Cytokines, endometriosis, interleukin-18, polymorphism
  • Trakya Üniversitesi Adresli: Evet

Özet

This study evaluated for the first time the relationship between interleukin-18 (IL-18) C607A genotypes and endometriosis in 135 women with endometriosis and 84 controls. In the study population, IL-18 -607A homozygote and A allele were positively correlated with the risk of developing endometriosis or the stage of endometriosis. © 2011 American Society for Reproductive Medicine, Published by Elsevier Inc.