Recurrent hydatidiform mole: When to stop ?

Ozbasli E., TAKMAZ Ö., GÜRKAN H., ALANAY Y., GÜNGÖR M., DEDE F. S.

Clinical and Experimental Obstetrics and Gynecology, cilt.47, sa.3, ss.424-426, 2020 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.31083/j.ceog.2020.03.5215
  • Dergi Adı: Clinical and Experimental Obstetrics and Gynecology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Sayfa Sayıları: ss.424-426
  • Anahtar Kelimeler: Familial hydatidiform mole, Genomic imprinting, NLRP7, Ovum donation
  • Trakya Üniversitesi Adresli: Evet

Özet

Recurrent hydatidiform mole (RHM) is defined as two or more repeated molar pregnancies in the same patient. Familial recurrent hydatidiform mole (FRHM) is a rare condition in which the patient has relatives with the same condition and mutations. Maternal mutations in the NLRP7 gene are mostly observed in RHM. The authors report a patient from Turkey with a history of seven molar pregnancies who had an aunt with similar obstetric history and NLRP7 mutations.