Optical biometry-based axial length alterations after intravitreal dexamethasone implant


ÖZAL S. A., KÜPELİ ÇINAR A., Ozal E., GÜRLÜ V.

ARQUIVOS BRASILEIROS DE OFTALMOLOGIA, cilt.82, sa.3, ss.195-199, 2019 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 82 Sayı: 3
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5935/0004-2749.20190040
  • Dergi Adı: ARQUIVOS BRASILEIROS DE OFTALMOLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.195-199
  • Trakya Üniversitesi Adresli: Evet

Özet

Purpose: To investigate changes in axial length after intravitreal dexamethasone implantation in patients with macular edema. Methods: We performed a prospective comparative study of 46 patients with unilateral macular edema, due to diabetic retinopathy, retinal vein occlusion, and non-infectious uveitis, who underwent dexamethasone implantation. The fellow eyes of the patients were considered the control group. The central macular thickness was measured by spectral-domain optical coherence tomography, and axial length was measured by IOLMaster 700 optical coherence biometry. We compared axial length and central macular thickness values within the groups. Results: In the study group, the baseline central macular thickness was 460.19 +/- 128.64 mu m, significantly decreasing to 324.00 +/- 79.84 mu m after dexamethasone implantation (p=0.000). No significant change in central macular thickness measurements was seen in the control group (p=0.244). In the study group, the baseline axial length was 23.16 +/- 0.68 mm, significantly increasing to 23.22 +/- 0.65 mm after dexamethasone implantation (p=0.039). However, the control group exhibited no significant change in axial length (p=0.123). Conclusions: In addition to significantly reducing central macular thickness measurements, intravitreal dexamethasone implantation also significantly changes optical biometry-based axial length measurements.