A new biflavonoid from Solanum dulcamara L. and investigation of anti-hyperglycaemic activity of its fruit extract
Natural Product Research, cilt.29, sa.4, ss.308-314, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 29 Sayı: 4
- Basım Tarihi: 2015
- Doi Numarası: 10.1080/14786419.2014.928878
- Dergi Adı: Natural Product Research
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.308-314
- Anahtar Kelimeler: anti-hyperglycaemic activity, biflavonoid, Solanum dulcamara, Solonaceae
- Trakya Üniversitesi Adresli: Evet
Özet
A new biflavone, 6,2′,3″,5″,4⌄-pentahydroxy-3,7″-biflavone, has been isolated from the fruits of Solanum dulcamara L., in addition to two known compounds, β-sitosterol and stigmasterol. Their structures were established on the basis of UV, IR, 1D, 2D NMR and HR-ESI-MS spectroscopic methods. The anti-hyperglycaemic effect of S. dulcamara was investigated using diabetic rats. The anti-hyperglycaemic activity of the fruit extract of S. dulcamara was presented for the first time in this study.