A new biflavonoid from Solanum dulcamara L. and investigation of anti-hyperglycaemic activity of its fruit extract


Sabudak T., KAYA O., Cukurova E.

Natural Product Research, cilt.29, sa.4, ss.308-314, 2015 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1080/14786419.2014.928878
  • Dergi Adı: Natural Product Research
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.308-314
  • Anahtar Kelimeler: anti-hyperglycaemic activity, biflavonoid, Solanum dulcamara, Solonaceae
  • Trakya Üniversitesi Adresli: Evet

Özet

A new biflavone, 6,2′,3″,5″,4⌄-pentahydroxy-3,7″-biflavone, has been isolated from the fruits of Solanum dulcamara L., in addition to two known compounds, β-sitosterol and stigmasterol. Their structures were established on the basis of UV, IR, 1D, 2D NMR and HR-ESI-MS spectroscopic methods. The anti-hyperglycaemic effect of S. dulcamara was investigated using diabetic rats. The anti-hyperglycaemic activity of the fruit extract of S. dulcamara was presented for the first time in this study.