Secondary amyloidosis causing nephrotic syndrome in a patient with non-Hodgkin's lymphoma: Quite a rare diagnosis


Pamuk G., Demir M., ÖRÜM H., TURGUT B., ÖZYILMAZ F., Tekgündüz E.

Clinical and Laboratory Haematology, cilt.28, sa.4, ss.259-261, 2006 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 4
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1111/j.1365-2257.2006.00795.x
  • Dergi Adı: Clinical and Laboratory Haematology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.259-261
  • Anahtar Kelimeler: Nephrotic syndrome, Non-Hodgkin's lymphoma, Secondary (AA-type) amyloidosis
  • Trakya Üniversitesi Adresli: Evet

Özet

Secondary amyloidosis is usually a complication of chronic inflammation. Amyloidosis cases during the course of non-Hodgkin's lymphoma (NHL) are usually of AL-type, only one NHL patient with secondary amyloidosis has been reported. Our 79-year-old male patient visited us with multiple lymphadenopathies, and he was diagnosed with nodal marginal zone B-cell lymphoma. After four cycles of combined chemotherapy; his urea, creatinine levels started to increase and he developed nephrotic-range proteinuria. His rectal biopsy demonstrated amyloid deposition in submucosal vessel walls. The patient has been under hemodialysis for 10 months and his lymphoma is still in partial remission. We presented this case because it is the second NHL patient who developed secondary amyloidosis during his disease course. © 2006 The Authors.